Lung Disease in Still's Disease

Monitoring & Treating Lung Disease in Still's Disease

Claudia Bracaglia Division of Rheumatology Ospedale Pediatrico Bambino Gesù Roma - Italy claudia.bracaglia@opbg.net

61 SD-LD patients from 21 Ped Rheum Centres European Registry on SD associated LD




European Registry on sJIA associated LD

61 SJIA-LD patients from 21 Ped Rheum Centres




SD associated LD Bambino Gesù experience




SD associated LD Bambino Gesù experience



*The reaction occurred after the first and the third administration of TCZ in 1 pt. LD developed before the drug reaction in 2 pts.



SD associated LD Bambino Gesù experience


• *2 pts were already on cyclosporine before LD diagnosis
• **3 pts switched from cyclosporine to MMF after LD diagnosis


SD associated LD Bambino Gesù experience


• *2 pts were already on cyclosporine before LD diagnosis
• **3 pts switched from cyclosporine to MMF after LD diagnosis

Outcome

• -1 pt improved with IL-1i and MMF
• -2 pts improved with MAS825
• -1 pt stable with emapalumab
• -1 pt worsened despite MAS825 and she now on emapalumab
• -1 pt developed LD on sirolimus
• -No pt developed LD complication
• -No pt died